| Game Name | System |
|---|
| Speak & Math (US, patent) | MAME |
| Speak & Read (US) | MAME |
| Speak & Rescue | MAME |
| Speak & Rescue (bootleg) | MAME |
| Speak & Spell (Japan) | MAME |
| Speak & Spell (UK, 1978 version) | MAME |
| Speak & Spell (UK, 1981 version) | MAME |
| Speak & Spell (US, 1978 version) | MAME |
| Speak & Spell (US, 1979 version) | MAME |
| Speak & Spell (US, 1980 version) | MAME |
| Speak & Spell (US, patent) | MAME |
| Speak & Spell Compact (US, 1981 version) | MAME |
| Speak & Spell Compact (US, 1982 version) | MAME |
| Speak & Write (UK) | MAME |
| Speak Easy (1982)(Quicksilva) | ZX Spectrum Z80 |
| Speakeasy | MAME |
| Speakeasy 4 Player | MAME |
| Speaker (1988)(Psian Software) | ZX Spectrum Z80 |
| Speakuhr (19xx)(-)(UNK-LANG) | ZX Spectrum Z80 |
| Spear Of Destiny (1992)(Formgen) | DOS |
| Spear of Destiny Mission Packs (1994)(FormGen Inc) | DOS |
| Spear of Destiny Mod New Gory Graphics (1992)(Formgen) | DOS |
| Spear of Destiny User Mod Super (1994)(Apogee Software) | DOS |
| Spec Daleks (19xx)(Sinclair Scene) | ZX Spectrum Z80 |
| Spec Ops - Airborne Commando (E) | PSX |
| Spec Ops - Airborne Commando (USA) | PSX2PSP |
| Spec Ops - Airborne Commando [NTSC-U] | PSX |
| Spec Ops - Covert Assault (E) | PSX |
| Spec Ops - Covert Assault (USA) | PSX2PSP |
| Spec Ops - Covert Assault [NTSC-U] | PSX |
| Spec Ops - Ranger Elite (E) | PSX |
| Spec Ops - Ranger Elite (USA) | PSX2PSP |
| Spec Ops - Ranger Elite [NTSC-U] | PSX |
| Spec Ops - Stealth Patrol (E) | PSX |
| Spec Ops - Stealth Patrol (USA) | PSX2PSP |
| Spec Ops - Stealth Patrol [NTSC-U] | PSX |
| Spec Ops 2 - Omega Squad (USA) | DC |
| Spec Ops II - Omega Squad (Europe)(En,Fr,De,It,Es) | DC |
| Speccode Program (demo-playable) (1992)(Blackwing Publishing)(PD)[needs STOS] | Atari ST |
| Speccy Demo (19xx)(Betasoft) | ZX Spectrum Z80 |
| Speccy Simon (1996)(Cheese Freak Software) | ZX Spectrum Z80 |
| Speccy Simon (1996)(Cheese Freak Software)[a] | ZX Spectrum Z80 |
| Special Brew (Maygay) (EPOCH) (1.1, set 1) | MAME |
| Special Brew (Maygay) (EPOCH) (1.1, set 2) | MAME |
| Special Brew (Maygay) (EPOCH) (1.3, set 3) | MAME |
| Special Brew (Maygay) (EPOCH) (1.3, set 4) | MAME |
| Special Brew (Maygay) (EPOCH) (1.4, set 10) | MAME |
| Special Brew (Maygay) (EPOCH) (1.4, set 9) | MAME |
| Special Brew (Maygay) (EPOCH) (1.5, set 5) | MAME |
| Special Brew (Maygay) (EPOCH) (1.5, set 6) | MAME |
| Special Brew (Maygay) (EPOCH) (1.6, set 7) | MAME |
| Special Brew (Maygay) (EPOCH) (1.6, set 8) | MAME |
| Special Brew (Maygay) (EPOCH) (1.8, set 11) | MAME |
| Special Brew (Maygay) (EPOCH) (1.8, set 12) | MAME |
| Special Brew (Maygay) (EPOCH) (1.9, set 13) | MAME |
| Special Brew (Maygay) (EPOCH) (1.9, set 14) | MAME |
| Special Circle Club (Barcrest) (MPU3, set 1) | MAME |
| Special Circle Club (Barcrest) (MPU3, set 2) | MAME |
| Special Circle Club (Barcrest) (MPU3, set 3) | MAME |
| Special Criminal Investigation (Europe) | SMS |
| Special Criminal Investigation (Europe) (Beta) | SMS |
| Special Criminal Investigation (Japan) | TG16 |
| Special Criminal Investigation (Japan) | MAME |
| Special Criminal Investigation (US) | MAME |
| Special Criminal Investigation (World set 1) | MAME |
| Special Criminal Investigation (World set 2) | MAME |
| Special Delivery (1984)(Dalali Software) | ZX Spectrum Z80 |
| Special Delivery (1984)(Dalali Software)[a] | ZX Spectrum Z80 |
| Special Delivery (1984)(Dalali) | Atari 800 |
| Special Delivery (19xx)(Muul, Madis)(FW) | Atari ST |
| Special Effects (Maygay, MV1 Video, set 1) | MAME |
| Special Effects (Maygay, MV1 Video, set 2) | MAME |
| Special Effects V2 (Maygay, MV1 Video) | MAME |
| Special Force | MAME |
| Special Forces | Amiga |
| Special Forces | MAME |
| Special Forces (1992)(MicroProse)(Disk 1 of 3) | Atari ST |
| Special Forces (1992)(MicroProse)(Disk 1 of 3)[cr Elite][b] | Atari ST |
| Special Forces (1992)(MicroProse)(Disk 2 of 3) | Atari ST |
| Special Forces (1992)(MicroProse)(Disk 2 of 3)[cr Elite][b] | Atari ST |
| Special Forces (1992)(MicroProse)(Disk 3 of 3) | Atari ST |
| Special Forces (1992)(MicroProse)(Disk 3 of 3)[cr Elite][b] | Atari ST |
| Special Forces (1992)(Microprose Software Inc) | DOS |
| Special Forces (Europe) | PS2 |
| Special Forces Elite Training | MAME |
| Special Forces II | MAME |
| Special Jinsei Game (NTSC-J) | GCN |
| Special Operations (1984)(M.C. Lothlorien) | ZX Spectrum Z80 |
| Special Operations (1984)(M.C. Lothlorien) | ZX Spectrum (TAP) |
| Special Operations (1984)(M.C. Lothlorien)[a] | ZX Spectrum Z80 |
| Special Operations (198x)(-) [UEF] | Electron |
| Special Operations (19xx)(M.C. Lothlorien)[SO start] [SSD] | BBC Micro |
| Special Operations (19xx)(M.C. Lothlorien)[a][SO start] [SSD] | BBC Micro |
| Special Operations (19xx)(M.C. Lothlorien)[h TSTH][bootfile] [SSD] | BBC Micro |
| Special Operations (UK) (1984) | CPC |
| Special Operations (UK) (1984) [a1] | CPC |
| Special Operations (UK) (1984) [a2] | CPC |
| Special Reserve (JPM) (MPS) | MAME |
| Special Tag Team Pro Wrestling (Japan) | NES |
| Special Tenanmon (1990)(Pekin Net) | X68K |
