| Game Name | System |
|---|
| Spacestation Silicon Valley (Europe) (En,Fr,De,Es,It,Nl,Sv) | GBC |
| Spaceward Ho (1993)(New World Computing) | DOS |
| Spaceway | Atari 800 |
| Spaceway (19xx)(Decibel)(Nl) | ZX Spectrum Z80 |
| Spaceway (19xx)(Decibel)(Nl)[a] | ZX Spectrum Z80 |
| Spaceway (19xx)(Decibel)(Nl)[a].TAP | ZX Spectrum (TAP) |
| Spacewrecked 14 Billion Light Years From Earth (1990)(Gremlin Interactive Ltd) | DOS |
| Spack (1989)(Esat Software)(fr)(Disk 1 of 3) | Atari ST |
| Spack (1989)(Esat Software)(fr)(Disk 2 of 3) | Atari ST |
| Spack (1989)(Esat Software)(fr)(Disk 3 of 3) | Atari ST |
| Spacola (1991)(Dongleware Verlags GmbH)(de)[a2][monochrom] | Atari ST |
| Spacola (1991)(Dongleware Verlags GmbH)(de)[a3][monochrom] | Atari ST |
| Spacola (1991)(Dongleware Verlags GmbH)(de)[a4][monochrom] | Atari ST |
| Spacola (1991)(Dongleware Verlags GmbH)(de)[a5][monochrom] | Atari ST |
| Spacola (1991)(Dongleware Verlags GmbH)(de)[a6][monochrom] | Atari ST |
| Spacola (1991)(Dongleware Verlags GmbH)(de)[a7][monochrom] | Atari ST |
| Spacola (1991)(Dongleware Verlags GmbH)(de)[a8][monochrom] | Atari ST |
| Spacola (1991)(Dongleware Verlags GmbH)(de)[a][monochrom] | Atari ST |
| Spacola (1991)(Dongleware Verlags GmbH)(de)[monochrom] | Atari ST |
| Spaghetti Western (1990)(Zeppelin Games) | ZX Spectrum Z80 |
| Spaghetti Western (1990)(Zeppelin Games) | ZX Spectrum (TAP) |
| Spaghetti Western (1990)(Zeppelin Games)[a] | ZX Spectrum Z80 |
| Spaghetti Western Simulator (UK) (1990) | CPC |
| Spain '82 | MAME |
| Spanisch Buddy (EU)(M3)(BAHAMUT) | NDS |
| Spanish for Everyone (U)(Independent) | NDS |
| Spanish_Study_Guide | Atari 800 |
| Spanish_Vocabulary_Builder | Atari 800 |
| Spanky's Quest (Europe) | GB |
| Spanky's Quest (Europe) | SNES |
| Spanky's Quest (USA) | SNES |
| Spanky's Quest (USA) | GB |
| Spanner (19xx)(-)(UNK-LANG) | ZX Spectrum Z80 |
| Spanner-X Endless Fire (1994)(Studio MM)(Disk 1 of 2)(Disk A) | X68K |
| Spanner-X Endless Fire (1994)(Studio MM)(Disk 2 of 2)(Disk B) | X68K |
| Spanner_A (1989)(MP-Networks) | X68K |
| Spannerman (UK) (1984) | CPC |
| Spannerman (UK) (1984) [a1] | CPC |
| Spare Change (1983)(Broderbund) | Atari 800 |
| Spare Change (19xx)(Broderbund)[cr] | Apple2 |
| Spare Change (UE) | C64 PP |
| Spare Tire | Atari 800 |
| Spark (19xx)(Mauro Rigoni)(UNK-LANG) | ZX Spectrum Z80 |
| Spark Man (v2.0, set 1) | MAME |
| Spark Man (v2.0, set 2) | MAME |
| Spark World (Japan) | SNES |
| SparkBugs | Atari 800 |
| Sparkee (19xx)(Vagabondo Entreprises) | Apple2 |
| Sparkling Feather | PCFX |
| Sparkster (Europe) | SNES |
| Sparkster (Europe) | Genesis |
| Sparkster (Japan) | SNES |
| Sparkster (USA) | SNES |
| Sparkster (USA) | Genesis |
| Sparkster - Rocket Knight Adventures 2 (Japan) | Genesis |
| Sparkz (prototype) | MAME |
| Spartacash (Maygay - Impulse) (EPOCH) (set 1) | MAME |
| Spartacash (Maygay - Impulse) (EPOCH) (set 2) | MAME |
| Spartacash (Maygay - Impulse) (EPOCH) (set 3) | MAME |
| Spartan - Total Warrior (Europe) (En,Es,It) | GCN |
| Spartan - Total Warrior (Europe) (En,Fr,De,Es,It) | PS2 |
| Spartan - Total Warrior (France) | GCN |
| Spartan - Total Warrior (Germany) | GCN |
| Spartan - Total Warrior (USA) | PS2 |
| Spartan Total Warrior | GCN |
| Spartan X (Japan) | MAME |
| Spartan X (Japan) | GB |
| Spartan X (Japan) | NES |
| Spartan X (Tecfri hardware bootleg) | MAME |
| Spartan X 2 (Japan) | NES |
| Spartan X 2 (Japan) [En by Abstract Crouton v1.0] (~Kung Fu 2) | NES |
| Spatial Hyperdrive | Amiga |
| Spatter (315-5099) | MAME |
| Spatter (315-xxxx) | MAME |
| Spawn (Europe) | SNES |
| Spawn (Japan) (Proto) | SNES |
| Spawn (USA) | SNES |
| Spawn (USA) | GBC |
| Spawn - Armageddon (Europe) (En,Fr,De,Es,It) | PS2 |
| Spawn - Armageddon (Europe) (En,Fr,De,Es,It) | GCN |
| Spawn - Armageddon (USA) | PS2 |
| Spawn - In the Demon's Hand (Japan) | DC |
| Spawn - In the Demon's Hand (USA) | DC |
| Spawn - In the Demon's Hand (United Kingdom) | DC |
| Spawn - The Eternal (Japan) | PSX |
| Spawn - The Eternal (USA) | PSX2PSP |
| Spawn - The Eternal [NTSC-U] | PSX |
| Spawn Armageddon | GCN |
| Spawn In the Demon's Hand (Rev B) | MAME |
| Spawn Of Evil (1983)(DK'Tronics) | ZX Spectrum (TAP) |
| Spawn Of Evil (1983)(DK'Tronics) | ZX Spectrum Z80 |
| Spawn Of Evil (1983)(DK'Tronics)(Sp) | ZX Spectrum Z80 |
| Spawn Of Evil (1983)(DK'Tronics)[a2] | ZX Spectrum Z80 |
| Spawn Of Evil (1983)(DK'Tronics)[a] | ZX Spectrum (TAP) |
| Spawn Of Evil (1983)(DK'Tronics)[a] | ZX Spectrum Z80 |
| Spawn Of Evil - Introduction (1983)(DK'Tronics) | ZX Spectrum Z80 |
| Spawn Of Evil - Introduction (1983)(DK'Tronics)[a] | ZX Spectrum Z80 |
| Speak & Help | MAME |
| Speak & Math (US, 1980 version) | MAME |
| Speak & Math (US, 1986 version) | MAME |
