| Game Name | System |
|---|
| Rampage (USA, Europe) | SMS |
| Rampart (Europe) | SMS |
| Rastan (USA, Europe) | SMS |
| Reggie Jackson Baseball (USA) | SMS |
| Renegade (Europe) | SMS |
| Rescue Mission (USA, Europe) | SMS |
| Road Rash (Europe) | SMS |
| RoboCop 3 (Europe) | SMS |
| RoboCop versus The Terminator (Europe) | SMS |
| Rocky (World) | SMS |
| Running Battle (Europe) | SMS |
| SDI (Japan) | SMS |
| Sagaia (Europe) | SMS |
| Sangokushi 3 (Korea) (Unl) | SMS |
| Sapo Xule - O Mestre do Kung Fu (Brazil) | SMS |
| Sapo Xule - S.O.S Lagoa Poluida (Brazil) | SMS |
| Sapo Xule vs. Os Invasores do Brejo (Brazil) | SMS |
| Satellite 7 (Japan) | SMS |
| Schtroumpfs Autour du Monde, Les (Europe) (En,Fr,De,Es) | SMS |
| Schtroumpfs Autour du Monde, Les (Europe) (En,Fr,De,Es) (Beta) | SMS |
| Scramble Spirits (Europe) | SMS |
| Secret Command (Europe) | SMS |
| Sega Chess (Europe) | SMS |
| Sega World Tournament Golf (Europe) | SMS |
| Seishun Scandal (Japan) | SMS |
| Sensible Soccer (Europe) | SMS |
| Shadow Dancer (Europe) | SMS |
| Shadow of the Beast (Europe) | SMS |
| Shanghai (USA, Europe) | SMS |
| Shanghai (USA, Europe) (Beta) | SMS |
| Shinobi (Japan) | SMS |
| Shinobi (USA, Europe) | SMS |
| Shooting Gallery (USA, Europe) | SMS |
| Simpsons, The - Bart vs. The Space Mutants (Europe) | SMS |
| Simpsons, The - Bart vs. The World (Europe) | SMS |
| Sitio do Picapau Amarelo (Brazil) | SMS |
| Slap Shot (Europe) | SMS |
| Slap Shot (USA) | SMS |
| Slap Shot (USA) (v1.1) | SMS |
| Smurfs, The (Europe) (En,Fr,De,Es) | SMS |
| Solomon no Kagi - Oujo Rihita no Namida (Japan) | SMS |
| Sonic Blast (Brazil) | SMS |
| Sonic Chaos (Europe) | SMS |
| Sonic Spinball (Europe) | SMS |
| Sonic The Hedgehog (USA, Europe) | SMS |
| Sonic The Hedgehog 2 (Europe) | SMS |
| Sonic The Hedgehog 2 (Europe) (v1.1) | SMS |
| Sonic's Edusoft (Unknown) (Proto) | SMS |
| Space Gun (Europe) | SMS |
| Space Harrier (Japan) | SMS |
| Space Harrier (USA, Europe) | SMS |
| Space Harrier 3-D (USA, Europe) | SMS |
| Space Harrier 3D (Japan) | SMS |
| Special Criminal Investigation (Europe) | SMS |
| Special Criminal Investigation (Europe) (Beta) | SMS |
| Speedball (Europe) (Mirrorsoft) | SMS |
| Speedball (Europe) (Virgin) | SMS |
| Speedball 2 (Europe) | SMS |
| SpellCaster (USA, Europe) | SMS |
| Spider-Man - Return of the Sinister Six (Europe) | SMS |
| Spider-Man vs. The Kingpin (USA, Europe) | SMS |
| Sports Pad Football (USA) | SMS |
| Sports Pad Soccer (Japan) | SMS |
| Spy vs Spy (Japan) | SMS |
| Spy vs. Spy (USA, Europe) | SMS |
| Star Wars (Europe) | SMS |
| Street Fighter II (Brazil) | SMS |
| Streets of Rage (Europe) | SMS |
| Streets of Rage II (Europe) | SMS |
| Strider (USA, Europe) | SMS |
| Strider II (Europe) | SMS |
| Submarine Attack (Europe) | SMS |
| Sukeban Deka II - Shoujo Tekkamen Densetsu (Japan) | SMS |
| Summer Games (Europe) | SMS |
| Summer Games (Europe) (Beta) | SMS |
| Super Basketball (USA) (Sample) | SMS |
| Super Kick Off (Europe) (En,Fr,De,Es,It,Nl,Pt,Sv) | SMS |
| Super Monaco GP (Europe) | SMS |
| Super Monaco GP (USA) | SMS |
| Super Off Road (Europe) | SMS |
| Super Racing (Japan) | SMS |
| Super Smash T.V. (Europe) | SMS |
| Super Space Invaders (Europe) | SMS |
| Super Tennis (USA, Europe) | SMS |
| Super Wonder Boy (Japan) | SMS |
| Super Wonder Boy - Monster World (Japan) | SMS |
| Superman - The Man of Steel (Europe) | SMS |
| T2 - The Arcade Game (Europe) | SMS |
| TV Colosso (Brazil) | SMS |
| Taito Chase H.Q. (Europe) | SMS |
| Taz in Escape from Mars (Brazil) | SMS |
| Taz-Mania (Europe) | SMS |
| Taz-Mania (Europe) (Beta) | SMS |
| Tecmo World Cup '92 (Europe) (Beta) | SMS |
| Tecmo World Cup '93 (Europe) | SMS |
| Teddy Boy (USA, Europe) | SMS |
| Teddy Boy Blues (Japan) | SMS |
| Teddy Boy Blues (Japan) (Proto) (Ep-MyCard) | SMS |
| Tennis Ace (Europe) | SMS |
| Tensai Bakabon (Japan) | SMS |
