| Game Name | System |
|---|
| Rock'n! Monster!! (Japan) | GB |
| Rockman World (Japan) | GB |
| Rockman World 2 (Japan) | GB |
| Rockman World 3 (Japan) | GB |
| Rockman World 4 (Japan) | GB |
| Rockman World 5 (Japan) | GB |
| Rodland (Europe) | GB |
| Rodland (Japan) | GB |
| Roger Clemens MVP Baseball (Japan) | GB |
| Roger Clemens MVP Baseball (USA) | GB |
| Rolan's Curse (USA) | GB |
| Rolan's Curse II (USA) | GB |
| Rubble Saver (Japan) | GB |
| Rubble Saver II (Japan) | GB |
| Rugrats Movie, The (USA) | GB |
| SD Command Gundam - G-Arms (Japan) | GB |
| SD Gundam Gaiden - Lacroan' Heroes (Japan) | GB |
| SD Hiryuu no Ken Gaiden (Japan) | GB |
| SD Hiryuu no Ken Gaiden 2 (Japan) | GB |
| SD Lupin III - Kinko Yaburi Daisakusen (Japan) | GB |
| SD Sengokuden - Kunitori Monogatari (Japan) | GB |
| SD Sengokuden 2 - Tenka Touitsu Hen (Japan) | GB |
| SD Sengokuden 3 - Chijou Saikyou Hen (Japan) | GB |
| Sa-Ga 2 - Hihou Densetsu (Japan) | GB |
| Sa-Ga 2 - Hihou Densetsu (Japan) (Rev A) | GB |
| Sa-Ga 3 - Jikuu no Hasha (Japan) | GB |
| Sagaia (Japan) | GB |
| Saigo no Nindou (Japan) | GB |
| Saint Paradise - Saikyou no Senshi-tachi (Japan) | GB |
| Sakigake!! Otoko Juku - Meioutou Kessen (Japan) | GB |
| Same Game (Japan) | GB |
| Samurai Shodown (USA, Europe) | GB |
| Sangokushi - Game Boy Ban (Japan) | GB |
| Sanrio Carnival (Japan) | GB |
| Sanrio Carnival (Japan) [En by Six Feet Under v1.2] | GB |
| Sanrio Carnival 2 (Japan) | GB |
| Sanrio Uranai Party (Japan) | GB |
| Schiffe Versenken (Germany) (En,Fr,De,Es) | GB |
| Scotland Yard (Japan) | GB |
| Sea Battle (Europe) (En,Fr,De,Es) | GB |
| SeaQuest DSV (USA, Europe) | GB |
| Seaside Volley (Japan) | GB |
| Seiken Densetsu (Japan) | GB |
| Selection - Erabareshi Mono (Japan) | GB |
| Selection I & II (Japan) | GB |
| Selection II - Ankoku no Fuuin (Japan) | GB |
| Sengoku Ninja-kun (Japan) | GB |
| Sensible Soccer - European Champions (Europe) | GB |
| Serpent (USA) | GB |
| Shadow Warriors (Europe) | GB |
| Shanghai (Japan) | GB |
| Shanghai (USA) | GB |
| Shanghai Pocket (Japan) | GB |
| Shaq Fu (USA) | GB |
| Shikinjou (Japan) | GB |
| Shin Keiba Kizoku Pocket Jockey (Japan) | GB |
| Shin Nihon Pro Wrestling - Toukon Sanjuushi (Japan) | GB |
| Shin SD Gundam Gaiden - Knight Gundam Monogatari (Japan) | GB |
| Shinri Game 2, The - Oosaka Hen (Japan) | GB |
| Shinri Game, The (Japan) | GB |
| Shinseiki GPX Cyber Formula (Japan) | GB |
| Shippo de Bun (Japan) | GB |
| Shippuu! Iron Leaguer (Japan) | GB |
| Shisenshou - Match-Mania (Japan) | GB |
| Shougi (Japan) | GB |
| Shougi Saikyou (Japan) | GB |
| Shougi Saikyou (Japan) (Rev A) | GB |
| Shounen Ashibe - Yuuenchi Panic (Japan) | GB |
| Shuyaku Sentai Irem Fighter (Japan) | GB |
| Side Pocket (World) | GB |
| Simpsons, The - Bart & the Beanstalk (USA, Europe) | GB |
| Simpsons, The - Bart vs. the Juggernauts (USA, Europe) | GB |
| Skate or Die - Bad 'N Rad (Europe) | GB |
| Skate or Die - Bad 'N Rad (USA) | GB |
| Skate or Die - Tour de Thrash (USA) | GB |
| Small Soldiers (USA, Europe) | GB |
| Smurfs Nightmare, The (Europe) (En,Fr,De,Es) | GB |
| Smurfs Travel the World, The (Europe) (En,Fr,De,Es) | GB |
| Smurfs, The (Europe) (En,Fr,De,Es) | GB |
| Smurfs, The (USA, Europe) (En,Fr,De) (Rev A) | GB |
| Sneaky Snakes (USA, Europe) | GB |
| Snoopy - Magic Show (Japan) | GB |
| Snoopy - Magic Show (USA, Europe) | GB |
| Snoopy no Hajimete no Otsukai (Japan) | GB |
| Snow Bros. Jr. (Europe) | GB |
| Snow Bros. Jr. (Japan) | GB |
| Snow Bros. Jr. (USA) | GB |
| Soccer (Europe) (En,Fr,De) | GB |
| Soccer (Japan) | GB |
| Soccer Boy (Japan) | GB |
| Soccer Mania (Japan, USA) | GB |
| Solar Striker (World) | GB |
| Soldam (Japan) | GB |
| Solitaire (Japan) | GB |
| Solitaire Funpak (USA, Europe) | GB |
| Solomon's Club (Europe) | GB |
| Solomon's Club (Japan) | GB |
| Solomon's Club (USA) | GB |
| Soreike! Amida-kun (Japan) | GB |
| Soreyuke! Speedy Gonzales (Japan) | GB |
