| Game Name | System |
|---|
| San Francisco Rush 2049 (USA) | GBC |
| Sangokushi - Game Boy Ban 2 (Japan) | GBC |
| Sanrio Timenet - Kako Hen (Japan) | GBC |
| Sanrio Timenet - Mirai Hen (Japan) | GBC |
| Santa Claus Junior (Europe) | GBC |
| Saru Puncher (Japan) | GBC |
| Scooby-Doo! - Classic Creep Capers (USA, Europe) | GBC |
| Scrabble (Europe) | GBC |
| Sei Hai Densetsu (Japan) | GBC |
| Seme COM Dungeon - Drururuaga (Japan) | GBC |
| Senkai Ibunroku Juntei Taisen - TV Animation Senkaiden Houshin Engi Yori (Japan) | GBC |
| Sesame Street Sports (USA) | GBC |
| Sgt. Rock - On the Frontline (USA) | GBC |
| Shadowgate Classic (USA, Europe) (En,Fr,De,Es,Sv) | GBC |
| Shadowgate Classic (USA, Europe) (En,Fr,De,Es,Sv) (Rev A) | GBC |
| Shadowgate Return (Japan) | GBC |
| Shaman King Card Game - Chou Senjiryakketsu - Funbari Hen (Japan) | GBC |
| Shaman King Card Game - Chou Senjiryakketsu - Meramera Hen (Japan) | GBC |
| Shamus (USA) | GBC |
| Shanghai Pocket (Japan) | GBC |
| Shanghai Pocket (USA) | GBC |
| Shanghai Pocket (USA, Europe) (Rev A) | GBC |
| Shantae (USA) | GBC |
| Shaun Palmer's Pro Snowboarder (USA) | GBC |
| Shin Megami Tensei Devil Children - Aka no Sho (Japan) | GBC |
| Shin Megami Tensei Devil Children - Kuro no Sho (Japan) | GBC |
| Shin Megami Tensei Devil Children - Shiro no Sho (Japan) | GBC |
| Shin Megami Tensei Trading Card - Card Summoner (Japan) | GBC |
| Shinseiki Evangelion - Mahjong Hokan Keikaku (Japan) | GBC |
| Shougi 2 (Japan) | GBC |
| Shougi 3 (Japan) | GBC |
| Shrek - Fairy Tale Freakdown (USA) (En,Fr,De,Es,It) | GBC |
| Shutokou Racing, The (Japan) | GBC |
| Simpsons, The - Night of the Living Treehouse of Horror (USA, Europe) | GBC |
| Smurfs Nightmare, The (Europe) (En,Fr,De,Es) | GBC |
| Smurfs Nightmare, The (USA) | GBC |
| Snobo Champion (Japan) | GBC |
| Snoopy Tennis (Europe) (En,Fr,De,Es,It,Nl) | GBC |
| Snoopy Tennis (Japan) | GBC |
| Snoopy Tennis (USA) (En,Fr,Es) | GBC |
| Snow White and the Seven Dwarfs (Europe) (En,Fr,De,Es,It,Nl,Sv,No,Da) | GBC |
| Snow White and the Seven Dwarfs (USA) | GBC |
| SnowCross (Europe) (En,Fr,De,Es,It,Pt) | GBC |
| Soccer Manager (Europe) (En,Fr,De,Es) | GBC |
| Solomon (Japan) | GBC |
| Soreike! Anpanman - 5-tsu no Tou no Ousama (Japan) | GBC |
| Soreike! Anpanman - Fushigi na Nikoniko Album (Japan) | GBC |
| Soukoban Densetsu - Hikari to Yami no Kuni (Japan) | GBC |
| Soul Getter - Houkago Bouken RPG (Japan) | GBC |
| Space Invaders (USA) | GBC |
| Space Invaders X (Japan) | GBC |
| Space Invasion & Karate Joe (Europe) (Unl) | GBC |
| Space Invasion (Europe) (Unl) | GBC |
| Space Marauder (USA) | GBC |
| Space-Net - Cosmo Blue (Japan) | GBC |
| Space-Net - Cosmo Red (Japan) | GBC |
| Spacestation Silicon Valley (Europe) (En,Fr,De,Es,It,Nl,Sv) | GBC |
| Spawn (USA) | GBC |
| Speedy Gonzales - Aztec Adventure (USA) | GBC |
| Spider-Man (France) | GBC |
| Spider-Man (Japan) | GBC |
| Spider-Man (USA, Europe) | GBC |
| Spider-Man 2 - The Sinister Six (USA) | GBC |
| Spirou Robbedoes - The Robot Invasion (Europe) (En,Fr,De,Es,It,Nl,Da) | GBC |
| SpongeBob SquarePants - Legend of the Lost Spatula (USA) | GBC |
| Spy vs. Spy (Europe) (En,Fr,De,Es,It,Nl,Sv) | GBC |
| Spy vs. Spy (Japan) | GBC |
| Spy vs. Spy (USA) | GBC |
| Star Ocean - Blue Sphere (Japan) | GBC |
| Star Wars Episode I - Obi-Wan's Adventures (Europe) (En,Fr,De,Es,It) | GBC |
| Star Wars Episode I - Obi-Wan's Adventures (USA) | GBC |
| Star Wars Episode I - Racer (USA, Europe) | GBC |
| Stranded Kids (Europe) (En,Fr,De) | GBC |
| Street Fighter Alpha - Warriors' Dreams (Europe) | GBC |
| Street Fighter Alpha - Warriors' Dreams (Japan) | GBC |
| Street Fighter Alpha - Warriors' Dreams (USA) | GBC |
| Stuart Little - The Journey Home (Europe) (Fr,De) | GBC |
| Stuart Little - The Journey Home (USA, Europe) | GBC |
| Super Black Bass - Real Fight (Japan) | GBC |
| Super Black Bass Pocket 3 (Japan) | GBC |
| Super Bombliss DX (Japan) | GBC |
| Super Breakout! (Europe) (En,Fr,De,Es,It,Nl) | GBC |
| Super Breakout! (USA) | GBC |
| Super Chinese Fighter EX (Japan) | GBC |
| Super Chinese Fighter EX (Japan) [En by Some Good Shit v0.99] | GBC |
| Super Doll Licca-chan - Kisekae Daisakusen (Japan) | GBC |
| Super Gals! Kotobuki Ran (Japan) | GBC |
| Super Gals! Kotobuki Ran 2 (Japan) | GBC |
| Super Me-Mail GB - Me-Mail Bear no Happy Mail Town (Japan) | GBC |
| Super Real Fishing (Japan) | GBC |
| Super Robot Pinball (Japan) | GBC |
| Super Robot Taisen - Link Battler (Japan) | GBC |
| Supercross Freestyle (Europe) (En,Fr,De,Es,It) | GBC |
| Supreme Snowboarding (Europe) (En,Fr,De) | GBC |
| Survival Kids (USA) | GBC |
| Survival Kids - Kotou no Boukensha (Japan) | GBC |
| Survival Kids 2 - Dasshutsu!! Futago Shima! (Japan) | GBC |
| Suzuki Alstare Extreme Racing (Europe) (En,Fr,De,Es,It,Nl) | GBC |
| Sweet Ange (Japan) | GBC |
| Swing (Germany) | GBC |
